Phenotypes Associated with This Genotype

Genotype
MGI:3582933

• Allelic Composition: Bicc1^jcpk/Bicc1^jcpk
• Genetic Background: involves: 101 * C3H * C57BL/6J * T STOCK

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

renal/urinary system

kidney cortex cyst ( J:36348 )

• cysts in the proximal and distal tubules

increased glomerular capsule space ( J:36348 )

• dilation of Bowman's space in 95% of glomeruli

liver/biliary system

abnormal bile duct morphology ( J:36348 )

• branched bile ductules are lined with hyperplastic epithelium

abnormal portal triad morphology ( J:36348 )

• the portal triad is expanded by hematopoietic cells and immature stromal cells

endocrine/exocrine glands

abnormal bile duct morphology ( J:36348 )

• branched bile ductules are lined with hyperplastic epithelium

growth/size/body

kidney cortex cyst ( J:36348 )

• cysts in the proximal and distal tubules

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
autosomal recessive polycystic kidney disease		DOID:0110861	OMIM:263200	J:36348