Mouse Genome Informatics
hm
    Bicc1jcpk-bpk/Bicc1jcpk-bpk
involves: BALB/c * CAST/EiJ
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• die between 14 and 21 days of age
• Background Sensitivity: lethality occurs earlier compared to homozygotes on an inbred BALB/c background which die at 4 to 5 weeks of age

renal/urinary system
• Background Sensitivity: kidney cysts at 14 days of age are similar those in homozygotes on an inbred BALB/c background at 24 to 28 days of age

liver/biliary system
• gall bladder dilation is common
• liver parenchyma is pale

growth/size
• significantly runted shortly after birth
• detected at 9 to 15 days of age
• Background Sensitivity: distension was not seen on an inbred BALB/c background until after 2 weeks of age

endocrine/exocrine glands
• gall bladder dilation is common

Mouse Models of Human Disease
OMIM IDRef(s)
Polycystic Kidney Disease, Autosomal Recessive; ARPKD 263200 J:36348