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Phenotypes Associated with This Genotype
Genotype
MGI:3582929
Allelic
Composition
Bicc1jcpk-bpk/Bicc1jcpk-bpk
Genetic
Background
involves: BALB/c * CAST/EiJ
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Bicc1jcpk-bpk mutation (0 available); any Bicc1 mutation (19 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• die between 14 and 21 days of age
• Background Sensitivity: lethality occurs earlier compared to homozygotes on an inbred BALB/c background which die at 4 to 5 weeks of age

renal/urinary system
• Background Sensitivity: kidney cysts at 14 days of age are similar those in homozygotes on an inbred BALB/c background at 24 to 28 days of age

liver/biliary system
• gall bladder dilation is common
• liver parenchyma is pale

growth/size/body
• significantly runted shortly after birth
• detected at 9 to 15 days of age
• Background Sensitivity: distension was not seen on an inbred BALB/c background until after 2 weeks of age

endocrine/exocrine glands
• gall bladder dilation is common

Mouse Models of Human Disease
OMIM ID Ref(s)
Polycystic Kidney Disease, Autosomal Recessive; ARPKD 263200 J:36348


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
04/26/2016
MGI 6.03
The Jackson Laboratory