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Phenotypes Associated with This Genotype
Genotype
MGI:3580913
Allelic
Composition		 Mxd3tm1Rne/Mxd3tm1Rne
Genetic
Background		 either: 129S4/SvJaeSor or (involves: 129S4/SvJaeSor * C57BL/6J)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Mxd3tm1Rne mutation (0 available); any Mxd3 mutation (10 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
increased cellular sensitivity to gamma-irradiation ( J:77649 )
• a 10% increase in the number of dead thymocytes 24 or 48 hours following gamma irradiation at 200, 500 and 1000 rads
• neural progenitor cells also demonstrated increased sensitivity

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory