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Phenotypes Associated with This Genotype
Genotype
MGI:3580460
Allelic
Composition		 Figntm1Frk/Figntm1Frk
Genetic
Background		 B6.129-Figntm1Frk/Frk
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Figntm1Frk mutation (1 available); any Fign mutation (39 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:64964 )
• of 9 homozygotes born only 3 survive to adulthood
prenatal lethality, incomplete penetrance ( J:64964 )
• of 106 pups from heterozygous intercrosses only 9 are homozygotes

behavior/neurological
head shaking ( J:64964 )
• all of the 3 homozygotes that survived to adulthood display head shaking, but not the circling that is found in fidget homozygotes

vision/eye
microphthalmia ( J:64964 )
• 100% of homozygotes have at least one small eye

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/14/2024
MGI 6.23 		The Jackson Laboratory