Phenotypes Associated with This Genotype

Genotype
MGI:3580167

• Allelic Composition: Reln^rl-5J/Reln^rl-5J
• Genetic Background: C3Fe(SWV) Mbp^shi-Reln^rl-5J/GrsrJ

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

behavior/neurological

ataxia ( J:98756 )

• from 2 weeks of age, mutant mice lean from one side to the other as they walk and frequently fall over sideways

nervous system

abnormal cortical marginal zone morphology ( J:98756 )

• the outer marginal layer of the cortex is populated by numerous ectopic cells

abnormal hippocampus layer morphology ( J:98756 )

• neurons of the mutant hippocampal gyrus are scattered throughout several irregular layers

abnormal stratification in cerebral cortex ( J:98756 )

• the cortical layers of mutant mice are scrambled

delaminated Purkinje cell layer ( J:98756 )

• Purkinje and granule cells of the mutant cerebellum are scrambled

delaminated cerebellar granule layer ( J:98756 )

• Purkinje and granule cells of the mutant cerebellum are scrambled

small cerebellum ( J:98756 )