Analysis Tools
nervous system
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• the hippocampus of a 9 week old mutant mouse was found to be enlarged
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• the brain of a 9 week old mutant mouse was found to have a severe deficit of Purkinje cells
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hearing/vestibular/ear
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• auditory brainstem response (ABR) testing revealed that, although mutant mice have a normal auditory threshold, their response latency is prolonged
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behavior/neurological
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• mutant mice exhibit moderate ataxia at 3-4 weeks of age, which is more pronounced by 5 weeks
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