Analysis Tools
hematopoietic system
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• peak numbers of embryonic erythroid colony forming units only about 50% normal numbers in the liver
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• although red cell counts are significantly reduced at birth they achieve near normal levels by 7 days of age
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• at birth the hematocrit is significantly lower (31.5 versus 43.4 in controls) but hematocrit reaches normal levles by 7 days of age
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• significantly smaller volumes at birth but normal by 7 days of age
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homeostasis/metabolism
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• delta aminolaevulinate synthetase activity in embryonic day 16 reticulocytes on a per cell basis is reduced to 53% of that of wild-type controls, and the activity in liver at embryonic day 13-14 is also reduced but to a lesser degree
• delta aminolaevulinate dehydratase activity in embryonic day 17-18 reticulocytes on a per cell basis is appriximately half of that in wild-type controls
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growth/size/body
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• slight reduction in body weight from birth through 60 days of age in both males and females
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pigmentation
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• white pigment covers an average of 22.9% and 23.6% of the ventrum in females and males respectively
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integument
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• white pigment covers an average of 22.9% and 23.6% of the ventrum in females and males respectively
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