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Phenotypes Associated with This Genotype
Genotype
MGI:3578281
Allelic
Composition		 Gsk3btm1Dral/Gsk3btm1Dral
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6 * CBA
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gsk3btm1Dral mutation (1 available); any Gsk3b mutation (111 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
homeostasis/metabolism
homeostasis/metabolism phenotype ( J:98263 )
N
• glucose and insulin levels were normal and mice were not glucose intolerant
• insulin no longer leads to inactivation of GSK3
abnormal glycogen homeostasis ( J:98263 )
• insulin unable to stimulate glycogen sythase activity in muscle

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory