About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3578234
Allelic
Composition		 Crebbptm1Pkb/Crebbptm1Pkb
Genetic
Background		 involves: 129P2/OlaHsd * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Crebbptm1Pkb mutation (2 available); any Crebbp mutation (99 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
postnatal lethality, incomplete penetrance ( J:98329 )
• about 40% lethality before weaning due to unknown causes, survivors are viable

hematopoietic system
decreased thymocyte number ( J:98329 )
• slight reduction in numbers

growth/size/body
decreased body size ( J:98329 )
• body size was reduced at 4 weeks of age

immune system
decreased thymocyte number ( J:98329 )
• slight reduction in numbers

endocrine/exocrine glands
decreased thymocyte number ( J:98329 )
• slight reduction in numbers

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory