Phenotypes Associated with This Genotype

Genotype
MGI:3577844

• Allelic Composition: Mme^tm1Cge/Mme^tm1Cge
• Genetic Background: B6.129S4-Mme^tm1Cge

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

increased susceptibility to type I hypersensitivity reaction ( J:66854 )

• allergic contact dermatitis

dermatitis ( J:66854 )

• increased allergic contact dermatitis, 80-120% higher than controls

homeostasis/metabolism

skin edema ( J:66854 )

• significant edema seen in sensitized animals after challenge

• increased inflammatory infiltrate, primarily of neutrophile and mononuclear cells

• epidermal hyperplasia between 16 and 72 hours after antigen challenge

integument

skin edema ( J:66854 )

• significant edema seen in sensitized animals after challenge

• increased inflammatory infiltrate, primarily of neutrophile and mononuclear cells

• epidermal hyperplasia between 16 and 72 hours after antigen challenge

dermatitis ( J:66854 )

• increased allergic contact dermatitis, 80-120% higher than controls