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Phenotypes Associated with This Genotype
Genotype
MGI:3577714
Allelic
Composition		 Irf9tm1Ttg/Irf9tm1Ttg
Genetic
Background		 B6.Cg-Irf9tm1Ttg
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Irf9tm1Ttg mutation (2 available); any Irf9 mutation (40 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
decreased interferon-alpha secretion ( J:97662 )
• CpG-A-induced production of interferon-alpha was abolished

skeleton
decreased bone mineral density ( J:84894 )
• mice exhibit a 40% decreased in bone volume in the trabecular bone compared to in wild-type mice

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
04/23/2024
MGI 6.23 		The Jackson Laboratory