Phenotypes Associated with This Genotype

Genotype
MGI:3577395

• Allelic Composition: Ppif^tm1Jmol/Ppif^tm1Jmol
• Genetic Background: involves: 129

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

cellular

abnormal mitochondrial physiology ( J:97660 )

• resistant to swelling and permeability transition induced by lower calcium ion levels

• greater capacity for calcium uptake

cardiovascular system

decreased myocardial infarct size ( J:97660 )

• 40% reduction in infarction area when subjected to cardiac ischemia/reperfusion injury

homeostasis/metabolism

decreased myocardial infarct size ( J:97660 )

• 40% reduction in infarction area when subjected to cardiac ischemia/reperfusion injury