Mouse Genome Informatics
tg
    Tg(MMTVneu)202Mul/0
FVB/N-Tg(MMTVneu)202Mul
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
tumorigenesis
• 72% of the tumor-bearing mice that lived to an age of 8 months or older developed metastases to the lung
• multiple foci of metastatic mammary adenocarcinoma lodged in pulmonary vessels were observed
• 50% incidence observed in both virgin and non-virgin females by 205 days of age; males appear phenotypically normal
• focal adenocarcinomas surrounded by hyperplastic mammary epithelium

Mouse Models of Human Disease
OMIM IDRef(s)
Breast Cancer 114480 J:56332