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Phenotypes Associated with This Genotype
Genotype
MGI:3577096
Allelic
Composition
Tg(MMTVneu)202Mul/0
Genetic
Background
FVB/N-Tg(MMTVneu)202Mul
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(MMTVneu)202Mul mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
tumorigenesis
• 72% of the tumor-bearing mice that lived to an age of 8 months or older developed metastases to the lung (J:56332)
• multiple foci of metastatic mammary adenocarcinoma lodged in pulmonary vessels were observed (J:56332)
• 72% of the tumor-bearing mice that lived to an age of 8 months or older developed metastases to the lung (J:56332)
• multiple foci of metastatic mammary adenocarcinoma lodged in pulmonary vessels were observed (J:56332)
• 50% incidence observed in both virgin and non-virgin females by 205 days of age; males appear phenotypically normal (J:56332)
• focal adenocarcinomas surrounded by hyperplastic mammary epithelium (J:56332)
• 50% incidence observed in both virgin and non-virgin females by 205 days of age; males appear phenotypically normal (J:56332)
• focal adenocarcinomas surrounded by hyperplastic mammary epithelium (J:56332)

Mouse Models of Human Disease
OMIM ID Ref(s)
Breast Cancer 114480 J:56332


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory