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Phenotypes Associated with This Genotype
Genotype
MGI:3577096
Allelic
Composition
Tg(MMTVneu)202Mul/0
Genetic
Background
FVB/N-Tg(MMTVneu)202Mul
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tg(MMTVneu)202Mul mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
integument
• 50% incidence observed in both virgin and non-virgin females by 205 days of age; males appear phenotypically normal
• focal adenocarcinomas surrounded by hyperplastic mammary epithelium

endocrine/exocrine glands
• 50% incidence observed in both virgin and non-virgin females by 205 days of age; males appear phenotypically normal
• focal adenocarcinomas surrounded by hyperplastic mammary epithelium

neoplasm
• 50% incidence observed in both virgin and non-virgin females by 205 days of age; males appear phenotypically normal
• focal adenocarcinomas surrounded by hyperplastic mammary epithelium
• 72% of the tumor-bearing mice that lived to an age of 8 months or older developed metastases to the lung
• multiple foci of metastatic mammary adenocarcinoma lodged in pulmonary vessels were observed

Mouse Models of Human Disease
OMIM ID Ref(s)
Breast Cancer 114480 J:56332


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory