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Phenotypes Associated with This Genotype
Genotype
MGI:3575500
Allelic
Composition
Brca1tm2Cxd/Brca1tm2Cxd
Tg(Fshr-cre)1Ldu/0
Genetic
Background
involves: C57BL/6 * C57BL/6J * DBA/2
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Brca1tm2Cxd mutation (4 available); any Brca1 mutation (115 available)
Tg(Fshr-cre)1Ldu mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
endocrine/exocrine glands
• at the ages between 12 and 20 months, 68% of mutant mice had grossly visible cysts attached to the ovary, within the wall of the uterine horns, or on the external surface of the uterine horns

renal/urinary system
• at the ages between 12 and 20 months, 2 out of 59 of mutant mice had renal cysts

reproductive system
• at the ages between 12 and 20 months, 68% of mutant mice had grossly visible cysts attached to the ovary, within the wall of the uterine horns, or on the external surface of the uterine horns

growth/size/body
• at the ages between 12 and 20 months, 68% of mutant mice had grossly visible cysts attached to the ovary, within the wall of the uterine horns, or on the external surface of the uterine horns
• at the ages between 12 and 20 months, 2 out of 59 of mutant mice had renal cysts


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory