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Phenotypes Associated with This Genotype
Genotype
MGI:3575396
Allelic
Composition
Map2tm1Noh/Map2tm1Noh
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Map2tm1Noh mutation (0 available); any Map2 mutation (109 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
growth/size/body
• although mice were viable, fertile, and grew normally, body weights were reduced 10-20%

nervous system
• apical dendrites of hippocampal neurons were significantly shorter than normal
• microtubule density was 23% less in Purkinje cell dendrites
• cross bridges between microtubules were thinner


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory