Phenotypes Associated with This Genotype

Genotype
MGI:3575021

• Allelic Composition: Sox18^Ra/Sox18⁺
• Genetic Background: Not Specified

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

darkened coat color ( J:86 )

• agouti pattern is modified, the entire coat being unusually dark

• due to abnormal hair growth exposing lower non-agouti hair shaft

integument

absent auchene hairs ( J:86 )

darkened coat color ( J:86 )

• agouti pattern is modified, the entire coat being unusually dark

• due to abnormal hair growth exposing lower non-agouti hair shaft

retarded hair growth ( J:86 )

• the first coat develops a little more slowly than normal

sparse hair ( J:86 )

• absence of auchene and zigzag hairs results in a coat with a thin, ragged appearance

abnormal zigzag hair morphology ( J:86 )

• nearly absent

abnormal hair follicle morphology ( J:12991 )

• growth of the late differentiating hair follicles which produce auchenes and zigzags is very retarded or arrested

homeostasis/metabolism

chylous ascites ( J:13089 )

• Background Sensitivity: two large group studies on different mixed background showed the frequency of ascites to be 11.1% and 17.8%