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Phenotypes Associated with This Genotype
Genotype
MGI:3574758
Allelic
Composition
Akt1tm1Mbb/Akt1tm1Mbb
Genetic
Background
involves: 129P2/OlaHsd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Akt1tm1Mbb mutation (1 available); any Akt1 mutation (37 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• cardiomyocytes were 19% smaller than in wildtype

growth/size/body
• reduced body size with smaller liver and heart and a 14% reduction in brain size that was proportional to the reduction in body size

liver/biliary system
• decreased number of cells in the liver

muscle
• cardiomyocytes were 19% smaller than in wildtype

nervous system
• decreased cell number in the brain


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory