Phenotypes Associated with This Genotype

Genotype
MGI:3574652

• Allelic Composition: Pcgf2^tm1Hko/Pcgf2⁺; Sf3b1^tm1Hko/Sf3b1⁺
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

skeleton

abnormal sternocostal joint morphology ( J:96358 )

• the detachment of the ribs of T7 from the sternum, representing an anterior shift of the sternum of one segment width

abnormal sternum ossification ( J:96358 )

• the formation of an additional ossification center in the sternum

vertebral transformation ( J:96358 )

thoracic vertebral transformation ( J:96358 )

• 75% exhibit T1 to T2 transformation

• 50% exhibit T13 to L1 transformation

cervical vertebral transformation ( J:96358 )

• 45% exhibit C7 to T1 transformation, and showed ectopic ribs associated with C7 mimicking perfect ribs and forming joints with the anteriorly shifted sternum

lumbar vertebral transformation ( J:96358 )

• 100% exhibit an L6 to S1 transformation