Mouse Genome Informatics
ot
    Dmdtm1.1Khan/Y
involves: C57BL/6 * CBA
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
cellular
• frequent muscle fiber necrosis peaking in 3-4 weeks old mice was observed (J:96210)

muscle
• severe muscular hypertrophy and dystrophy were observed in the skeletal muscle and diaphragm (J:96210)
• degenerating muscle fibers with cellular infiltration and regenerated muscle appeared at 4 weeks of age (J:96210)
• extensive myofiber degeneration in diaphragm muscle at 4 weeks of age (J:96210)

reproductive system
• hemizygous males were viable and normal in body size and external appearance, but they did not reproduced despite intensive mating (J:96210)

Mouse Models of Human Disease
OMIM IDRef(s)
Muscular Dystrophy, Duchenne Type; DMD 310200 J:96210