Mouse Genome Informatics
ot
    Dmdtm1.1Khan/Y
involves: C57BL/6 * CBA
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
muscle
• severe muscular hypertrophy and dystrophy were observed in the skeletal muscle and diaphragm
• degenerating muscle fibers with cellular infiltration and regenerated muscle appeared at 4 weeks of age
• extensive myofiber degeneration in diaphragm muscle at 4 weeks of age
• frequent muscle fiber necrosis peaking in 3-4 weeks old mice was observed

reproductive system
• hemizygous males were viable and normal in body size and external appearance, but they did not reproduced despite intensive mating

Mouse Models of Human Disease
OMIM IDRef(s)
Muscular Dystrophy, Duchenne Type; DMD 310200 J:96210