growth/size/body
• injection of insulin caused more profound hypoglycemia in heterozygotes than in wild-type mice
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homeostasis/metabolism
• injection of D-glucose resulted in a more rapid glucose clearance in heterozygous compared to wild-type
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• in response to insulin stimulation GLUT4 glucose transporter and glycogen synthesis are increased more profoundly in skeletal muscle of heterozygotes compared to wild-type mice
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