About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3531164
Allelic
Composition		 Hmgb1tm1Meb/Hmgb1tm1Meb
Genetic
Background		 C.129P2-Hmgb1tm1Meb
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hmgb1tm1Meb mutation (0 available); any Hmgb1 mutation (16 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
chromosome breakage ( J:95963 )
• cultured embryonic fibroblast cells from homozygous mice grow normally, however they show high levels of aneuploidy and spontaneous chromosome aberrations, and display higher rates of damage after UV irradiation

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/06/2026
MGI 6.24 		The Jackson Laboratory