Phenotypes Associated with This Genotype

Genotype
MGI:3530651

• Allelic Composition: F2rl1^tm1Bpd/F2rl1^tm1Bpd
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

immune system

decreased inflammatory response ( J:124648 )

• absence of human trypsin IV and rat p23 induced edema and granulocyte infiltration after intraplantar injection

increased inflammatory response ( J:96196 )

• observed a greater inflammatory response than in controls when pancreatitis was experimentally induced in mice

increased susceptibility to induced pancreatitis ( J:96196 )

• severity of experimentally induced pancreatitis was increased compared to wild-type with more acinar cell vacuolization, intralobular edema, and acinar cell necrosis and a greater inflammatory response

endocrine/exocrine glands

increased susceptibility to induced pancreatitis ( J:96196 )

• severity of experimentally induced pancreatitis was increased compared to wild-type with more acinar cell vacuolization, intralobular edema, and acinar cell necrosis and a greater inflammatory response

behavior/neurological

abnormal pain threshold ( J:124648 )

• absence of human trypsin IV and rat p23 induced thermal hyperalgesia and mechanical allodynia and hyperalgesia