Mouse Genome Informatics
cn
    Atrxtm1Rjg/Y
Tg(Nes-cre)2472Pick/0

involves: 129P2/OlaHsd * C57BL/6 * FVB/N
Key:
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• reduced postnatal survival similar to Atrx hemizygotes that are heterozygous for Foxg1tm1(cre)Skm

growth/size/body
• mutants are smaller at birth

nervous system
• not as severe as in Atrx hemizygotes that are heterozygous for Foxg1tm1(cre)Skm
• the frontal cortex is reduced in size especially in the caudal-medial cortex similar to Atrx hemizygotes that are heterozygous for Foxg1tm1(cre)Skm but the severity of loss is decreased

Mouse Models of Human Disease
OMIM IDRef(s)
Alpha-Thalassemia/Mental Retardation Syndrome, X-Linked; ATRX 301040 J:95953