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Phenotypes Associated with This Genotype
Genotype
MGI:3529284
Allelic
Composition
Fgf2tm1Doe/Fgf2tm1Doe
Fgf9tm1Dor/Fgf9tm1Dor
Genetic
Background
involves: C57BL/6J
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fgf2tm1Doe mutation (1 available); any Fgf2 mutation (20 available)
Fgf9tm1Dor mutation (0 available); any Fgf9 mutation (17 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
cardiovascular system
• at E12.5 the atria are enlarged
• at E12.5, the hearts are smaller with a disproportionate loss of tissue at the apex of the heart and in the regions around the interventricular groove; however, the patterning of the ventricles, septum, valves, and outflow tract are normal
• double homozygotes are indistinguishable from Fgf9 single homozygotes


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory