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Phenotypes Associated with This Genotype
Genotype
MGI:3527278
Allelic
Composition		 Kcnn2tm1.1Jpad/Kcnn2tm1.1Jpad
Genetic
Background		 Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Kcnn2tm1.1Jpad mutation (1 available); any Kcnn2 mutation (43 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
nervous system
abnormal action potential ( J:187145 )
• prior to and after apamin treated dopamine neurons exhibit a higher mean inter-spike interval compared with wild-type neurons
abnormal afterhyperpolarization ( J:94941 )
• the apamin sensitive component of the medium afterhyperpolarization current is absent from CA1 neurons, however hippocampal morphology and slow afterhyperpolarization currents are normal

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
05/28/2024
MGI 6.13 		The Jackson Laboratory