About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3526401
Allelic
Composition		 Sphk1tm1Rlp/Sphk1tm1Rlp
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sphk1tm1Rlp mutation (2 available); any Sphk1 mutation (30 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
normal phenotype
no abnormal phenotype detected ( J:95168 )
• homozygous null mice are viable, fertile, and without any obvious abnormalities, however serum and plasma levels of sphingosine-1-phosphate were reduced to less than 50% of wild-type

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
01/28/2026
MGI 6.24 		The Jackson Laboratory