Mouse Genome Informatics
hm
    vsd/vsd
C57BL/6J-vsd
Key:
phenotype observed in females WTSI Wellcome Trust Sanger Institute
phenotype observed in males EuPh Europhenome
N normal phenotype
       
mortality/aging
• pups die at birth

cardiovascular system
• enlarged peritruncal coronary veins are found at the base of the outflows
• congested atria are seen
• small muscular ventricular septal defects are seen
• outflow regurgitation is seen

growth/size

limbs/digits/tail
• mutants have only 3 digits on the front paws and in some cases the third digit is bifurcated
• the forelimbs are abnormally flexed towards the chest

embryogenesis

Mouse Models of Human Disease
OMIM IDRef(s)
Clubfoot, Congenital, with or without Deficiency of Long Bones and/or Mirror-Image Polydactyly; CCF 119800 J:94456
Holt-Oram Syndrome; HOS 142900 J:94456