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Phenotypes Associated with This Genotype
Genotype
MGI:3522506
Allelic
Composition		 Dll4tm1Nwg/Dll4+
Genetic
Background		 involves: 129S6/SvEvTac * C57BL/6NTac * ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Dll4tm1Nwg mutation (0 available); any Dll4 mutation (26 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
mortality/aging
embryonic lethality during organogenesis, incomplete penetrance ( J:94740 )
• over half of all heterozygous embryos die around E10.5
• Background Sensitivity: survival is increased compared to heterozygotes on a mixed 129, C57BL/6 background

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/09/2024
MGI 6.23 		The Jackson Laboratory