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Phenotypes Associated with This Genotype
Genotype
MGI:3512550
Allelic
Composition
Gt(ROSA)26Sortm1(Akt1/EGFP)Glas/Gt(ROSA)26Sor+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Gt(ROSA)26Sortm1(Akt1/EGFP)Glas mutation (0 available); any Gt(ROSA)26Sor mutation (944 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
adipose tissue
• after treatment with tamoxifen a significant decrease in adipose tissue deposits is seen

muscle
• a significant increase in mean skeletal muscle fiber diameter is seen in tamoxifen-treated mutants however the number of muscle fibers does not increase
• after treatment with tamoxifen a significant increase in muscle weight is seen
• after treatment with tamoxifen a significant increase in skeletal muscle size is seen


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/30/2024
MGI 6.23
The Jackson Laboratory