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Phenotypes Associated with This Genotype
Genotype
MGI:3512004
Allelic
Composition
Ddb2tm1Pra/Ddb2tm1Pra
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ddb2tm1Pra mutation (0 available); any Ddb2 mutation (15 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
mortality/aging
• 100% died between 20 and 26 months of age

neoplasm
• broad spectrum of tumors found in mice dying between 20 and 26 months of age
• high susceptibility to UV induced tumor incidence
• develop very aggressive tumors, death occurs within 3 weeks of tumor development

Mouse Models of Human Disease
OMIM ID Ref(s)
Xeroderma Pigmentosum, Complementation Group E 278740 J:95633


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/12/2016
MGI 6.04
The Jackson Laboratory