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Phenotypes Associated with This Genotype
Genotype
MGI:3510920
Allelic
Composition
Tg(ALB-cre,CMV-rtTA)#Wcyy/0
Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy/0
Genetic
Background
involves: ICR
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• serum cholesterol is reduced 35-40% 5 days after doxycycline treatment compared to untreated controls (J:93624)
• serum cholesterol is reduced 35-40% 5 days after doxycycline treatment compared to untreated controls (J:93624)

liver/biliary system
• lipid accumulation is seen only in the liver after doxycycline treatment (J:93624)
• lipid accumulation is seen only in the liver after doxycycline treatment (J:93624)

Mouse Models of Human Disease
OMIM ID Ref(s)
Tangier Disease; TGD 205400 J:93624


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory