Phenotypes Associated with This Genotype

Genotype
MGI:3056288

• Allelic Composition: Ctnnb1^tm1Yy/Ctnnb1^tm1Yy; Tg(Col2a1-cre)1Bhr/0
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

neonatal lethality, complete penetrance ( J:93028 )

• mutants die shortly after birth

craniofacial

domed cranium ( J:93028 )

limbs/digits/tail

short limbs ( J:93028 )

skeleton

domed cranium ( J:93028 )

fused synovial joints ( J:93028 )

• the calcaneus is fused to the cuboid and the navicular is partially fused to the intermediate cuneiforms at E15.5