Phenotypes Associated with This Genotype

Genotype
MGI:3055950

• Allelic Composition: Tg(SLC2A4-OGT)15Jaha/0
• Genetic Background: involves: C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

increased circulating insulin level ( J:93113 )

• in the random fed state hyperinsulinemia is seen in males and to a lesser degree in females

increased circulating leptin level ( J:93113 )

♂ • circulating leptin is increased in transgenic males but not in females

insulin resistance ( J:93113 )

♂ • insulin resistance is seen in transgenic males but not in females

♂ • glucose sensitivity is normal in transgenic males and females