Phenotypes for Myf5 Myod1 MGI:3055413 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Myf5^tm1Pas/Myf5^tm1Pas Myod1^tm1Jae/Myod1^tm1Jae
Genetic Background	involves: 129 * C57BL/6 * DBA/2

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Myf5^tm1Pas mutation (1 available); any Myf5 mutation (17 available)
Myod1^tm1Jae mutation (2 available); any Myod1 mutation (23 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

postnatal lethality, complete penetrance ( J:92799 )

• double homozygous mutants display postnatal lethality

muscle

abnormal myogenesis ( J:92799 )

• no skeletal myogenesis is seen at any developmental stage

absent skeletal muscle ( J:92799 )

• mutants lack skeletal muscle throughout the body including the head

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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