Phenotypes for Stat5b Tg(Wap-cre)11738Mam MGI:3055367 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Stat5b^tm1Mam/Stat5b^tm1Mam Tg(Wap-cre)11738Mam/0
Genetic Background	involves: 129S6/SvEvTac * Black Swiss

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Stat5b^tm1Mam mutation (0 available); any Stat5b mutation (33 available)
Tg(Wap-cre)11738Mam mutation (3 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

endocrine/exocrine glands

abnormal mammary gland alveolus morphology ( J:92770 )

• the number of alveoli is reduced, however females are able to successfully nurse their pups

• the alveoli that are present are distended

increased mammary gland apoptosis ( J:92770 )

• increased apoptosis is seen in the mammary epithelium during late pregnancy

integument

abnormal mammary gland alveolus morphology ( J:92770 )

• the number of alveoli is reduced, however females are able to successfully nurse their pups

• the alveoli that are present are distended

increased mammary gland apoptosis ( J:92770 )

• increased apoptosis is seen in the mammary epithelium during late pregnancy

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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