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Phenotypes Associated with This Genotype
Genotype
MGI:3055174
Allelic
Composition
Tnfrsf8tm1Mak/Tnfrsf8tm1Mak
Genetic
Background
involves: C57BL/6
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Tnfrsf8tm1Mak mutation (1 available); any Tnfrsf8 mutation (42 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• increased host survival is seen after transplant of 0.3x105 mutant CD4+ T cells into sublethally irradiated bm12 recipients compared to transplant of wild-type T cells
• no difference in survival is seen at higher CD4+ T cell concentrations or when CD8+ T cells are used


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
01/06/2026
MGI 6.24
The Jackson Laboratory