Phenotypes Associated with This Genotype

Genotype
MGI:3052994

• Allelic Composition: Dspd/Dspd⁺
• Genetic Background: involves: C3H * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

reproductive system

oligozoospermia ( J:89381 )

♂

abnormal sperm head morphology ( J:89381 )

♂ • almost all of the spermatozoa found in the epididymis have misshapen heads

abnormal spermiogenesis ( J:89381 )

♂ • spermatids prematurely detach from the seminiferous epithelium

♂ • the number of elongated spermatids is decreased compared to wild-type

♂ • multinucleated spermatids are seen

reduced female fertility ( J:89381 )

♀ • heterozygous females have reduced litter sizes

male infertility ( J:89381 )

♂ • no offspring are obtained despite normal mating behavior however in vitro fertilization with round spermatids produces offspring

cellular

oligozoospermia ( J:89381 )

♂

abnormal sperm head morphology ( J:89381 )

♂ • almost all of the spermatozoa found in the epididymis have misshapen heads