Phenotypes Associated with This Genotype

Genotype
MGI:3052679

• Allelic Composition: Pbx1^tm1Mlc/Pbx1⁺
• Genetic Background: involves: 129S6/SvEvTac * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

endocrine/exocrine glands

abnormal pancreatic islet morphology ( J:75811 )

• abnormal clustering of islets

decreased insulin secretion ( J:75811 )

• inappropriate decrease in insulin secretion following glucose challenge

growth/size/body

decreased body size ( J:70684 )

homeostasis/metabolism

decreased insulin secretion ( J:75811 )

• inappropriate decrease in insulin secretion following glucose challenge

impaired glucose tolerance ( J:75811 )

increased insulin sensitivity ( J:75811 )