Phenotypes Associated with This Genotype

Genotype
MGI:3052474

• Allelic Composition: Tg(Dct-SOX9)aCeb/0
• Genetic Background: involves: pFVB/K

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

pigmentation

diluted coat color ( J:91429 )

• a lighter than normal coat color is seen

white spotting ( J:91429 )

• distinctive white spots are seen

reproductive system

reproductive system phenotype ( J:91429 )

N • no female to male sex reversal is seen in these transgenics unlike in Ods^{Tg(Tyr)1220Ove}

vision/eye

iris coloboma ( J:91429 )

• iris coloboma similar to that seen in Ods^{Tg(Tyr)1220Ove} is seen

cataract ( J:91429 )

microphthalmia ( J:91429 )

• caused by inappropriate expression of Sox9 in the retinal pigmented epithelium

integument

diluted coat color ( J:91429 )

• a lighter than normal coat color is seen

white spotting ( J:91429 )

• distinctive white spots are seen