Phenotypes Associated with This Genotype

Genotype
MGI:3052160

• Allelic Composition: Tg(Myog-Ntf3)5160Wds/0
• Genetic Background: involves: C57BL/6 * CBA * CF-1

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

nervous system

abnormal muscle spindle morphology ( J:43444 )

• abnormal clusters of spindle bundles are seen

abnormal dorsal root ganglion morphology ( J:43444 )

• a slight but significant increase in the overall number of dorsal root ganglia neurons at L4 is seen in 4 - 5 week old mice

• a 24% increase in the number of myelinated axons compared to wild-type littermates is seen

abnormal proprioceptive neuron morphology ( J:43444 )

• the number of proprioceptive neurons and spindle bundles are increased in most skeletal muscles except the soleus and external hallucis longus muscles

muscle

abnormal muscle spindle morphology ( J:43444 )

• abnormal clusters of spindle bundles are seen