Phenotypes for Ube2a Ube2b MGI:3051838 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Ube2a^tm1Agr/Y Ube2b^tm1Jhjh/Ube2b⁺
Genetic Background	involves: 129P2/OlaHsd * FVB/N

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Ube2a^tm1Agr mutation (0 available); any Ube2a mutation (6 available)
Ube2b^tm1Jhjh mutation (0 available); any Ube2b mutation (20 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

mortality/aging

prenatal lethality, incomplete penetrance ( J:91848 )

• fewer than expected male mutants are found at birth

growth/size/body

decreased birth weight ( J:91848 )

• body weight is markedly reduced at birth

decreased body weight ( J:91848 )

• a body weight reduction of about 37% compared to wild-type littermates is seen at 10 days of age

reproductive system

reproductive system phenotype ( J:91848 )

N	• males are fertile

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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