Phenotypes for Hoxb1 Tfap2a MGI:3050415 MGI Mouse

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Phenotypes Associated with This Genotype

Allelic Composition	Hoxb1^tm5Mrc/Hoxb1^tm7Mrc Tfap2a^tm1(cre)Moon/Tfap2a⁺
Genetic Background	involves: 129S1/Sv * 129X1/SvJ

Find Mice

Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Hoxb1^tm5Mrc mutation (0 available); any Hoxb1 mutation (24 available)
Hoxb1^tm7Mrc mutation (0 available); any Hoxb1 mutation (24 available)
Tfap2a^tm1(cre)Moon mutation (1 available); any Tfap2a mutation (39 available)

♀	phenotype observed in females
♂	phenotype observed in males
N	normal phenotype

behavior/neurological

behavior/neurological phenotype ( J:91364 )

N	• no behavioral abnormalities are seen

nervous system

decreased motor neuron number ( J:91364 )

• the average number of motor neurons is significantly reduced in mutants compared to wild-type mice although not to the same extent as in compound heterozygous mutants carrying Tg(Wnt1-cre)11Rth

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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