Phenotypes Associated with This Genotype

Genotype
MGI:3050243

• Allelic Composition: Tg(PDGFB-Hyou1)#Tam/0
• Genetic Background: involves: BALB/c * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

homeostasis/metabolism

decreased susceptibility to neuronal excitotoxicity ( J:91396 )

• kainate causes reduced excitotoxicity induced neuronal cell death resulting from excitotoxicity in transgenics compared to wild-type mice

abnormal response to CNS ischemic injury ( J:67962 )

• 24 hours after permanent middle cerebral artery occlusion neurological deficit and infarct volume are significantly reduced

nervous system

decreased susceptibility to neuronal excitotoxicity ( J:91396 )

• kainate causes reduced excitotoxicity induced neuronal cell death resulting from excitotoxicity in transgenics compared to wild-type mice

abnormal response to CNS ischemic injury ( J:67962 )

• 24 hours after permanent middle cerebral artery occlusion neurological deficit and infarct volume are significantly reduced

cellular

decreased susceptibility to neuronal excitotoxicity ( J:91396 )

• kainate causes reduced excitotoxicity induced neuronal cell death resulting from excitotoxicity in transgenics compared to wild-type mice