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Phenotypes Associated with This Genotype
Genotype
MGI:3047777
Allelic
Composition
Avpr2tm1Jwe/Avpr2+
Genetic
Background
involves: 129S1/Sv * 129X1/SvJ * CF-1
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Avpr2tm1Jwe mutation (0 available); any Avpr2 mutation (1 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
behavior/neurological
• mice drank about two times more water than controls

homeostasis/metabolism
• urine hypoosmolality

renal/urinary system
• urine hypoosmolality
• reduced urine concentrating ability
• mice produced about three times more urine than controls

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
nephrogenic diabetes insipidus DOID:12387 J:66094


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/12/2024
MGI 6.23
The Jackson Laboratory