Analysis Tools
reproductive system
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• male but not female mutants are infertile
• sperm numbers, morphology and motility are normal
• increased DNA strand breaks and altered chromatin structure are seen in sperm from homozygous mutants
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• no cleaved embryos are recovered 1.5 days after mating of homozygous males to wild-type females
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• acrosome reaction does not increase in response to a calcium ionophore
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