Phenotypes Associated with This Genotype

Genotype
MGI:3047332

• Allelic Composition: Myb^tm1Cgn/Myb^tm1Cgn; Tg(Lck-cre)548Jxm/0
• Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

hematopoietic system

thymus hypoplasia ( J:91122 )

• thymus cellularity is reduced about 75%

decreased double-positive T cell number ( J:91122 )

• the absolute number of double positive cells is decreased about 80%

decreased CD4-positive, alpha-beta T cell number ( J:91122 )

• the absolute number of CD4 single positive cells is decreased about 80%

immune system

thymus hypoplasia ( J:91122 )

• thymus cellularity is reduced about 75%

decreased double-positive T cell number ( J:91122 )

• the absolute number of double positive cells is decreased about 80%

decreased CD4-positive, alpha-beta T cell number ( J:91122 )

• the absolute number of CD4 single positive cells is decreased about 80%

endocrine/exocrine glands

thymus hypoplasia ( J:91122 )

• thymus cellularity is reduced about 75%