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Phenotypes Associated with This Genotype
Genotype
MGI:3047280
Allelic
Composition		 Nlrc4tm1Vmd/Nlrc4tm1Vmd
Genetic
Background		 C57BL/6N-Nlrc4tm1Vmd
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Nlrc4tm1Vmd mutation (1 available); any Nlrc4 mutation (67 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
cellular
abnormal cell death ( J:91292 )
• caspase dependent cell death resulting from infection with Salmonella typhimurium reduced to minor levels

immune system
decreased interleukin-1 beta secretion ( J:91292 )
• negligible amounts of Il-1beta produced when infected with Salmonella typhimurium

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory