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Phenotypes Associated with This Genotype
Genotype
MGI:3047272
Allelic
Composition
Trgc1tm1.2Dhr/Trgc1tm1.2Dhr
Genetic
Background
either: 129S4/SvJae or (involves: 129S4/SvJae * C57BL/6)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Trgc1tm1.2Dhr mutation (0 available); any Trgc1 mutation (4 available)
phenotype observed in females
phenotype observed in males
N normal phenotype
immune system
• gamma delta T cells (dendritic epidermal T cells) are absent from the skin however normal gamma delta T cell populations are normal in the spleen and intestinal epithelium
• fewer than expected gamma delta T cells are found in the fetal thymus from E15 to E17

hematopoietic system
• gamma delta T cells (dendritic epidermal T cells) are absent from the skin however normal gamma delta T cell populations are normal in the spleen and intestinal epithelium
• fewer than expected gamma delta T cells are found in the fetal thymus from E15 to E17


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/31/2026
MGI 6.24
The Jackson Laboratory