Phenotypes Associated with This Genotype

Genotype
MGI:3047260

• Allelic Composition: Hprt1^{tm2(UAS-Bmp4)Bhr}/Hprt1⁺; Tg(Wnt1-GAL4)1Rth/0
• Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

mortality/aging

embryonic lethality during organogenesis, incomplete penetrance ( J:91296 )

♀ • many transgenic embryos die between E11.5 and E12.5

cardiovascular system

abnormal blood vessel morphology ( J:91296 )

♀ • at E11.5 embryos display ectopic blood vessel formation

hemorrhage ( J:91296 )

♀ • at E11.5 embryos display midbrain hemorrhage

growth/size/body

embryonic growth retardation ( J:91296 )

♀ • by E11.5 embryos are growth retarded

vision/eye

abnormal eye morphology ( J:91296 )

♀ • at E11.5 eye abnormalities are seen

nervous system

exencephaly ( J:91296 )

♀ • at E11.5 embryos display midbrain exencephaly

embryo

embryonic growth retardation ( J:91296 )

♀ • by E11.5 embryos are growth retarded