About   Help   FAQ
Phenotypes Associated with This Genotype
Genotype
MGI:3047101
Allelic
Composition		 Fancatm1Wong/Fancatm1Wong
Genetic
Background		 either: 129S6/SvEvTac or (involves: 129S6/SvEvTac * CD-1)
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Fancatm1Wong mutation (0 available); any Fanca mutation (81 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
neoplasm
neoplasm ( J:85108 )
N
• while not statistically significant due to small sample size, tumors were observed in 33% of mice on a mixed genetic background involving 129S6/SvEvTac and CD1 and in 11.7% of mice on a 129S6/SvEvTac coisogenic background; whereas no tumors were observed in wild-type mice

endocrine/exocrine glands
seminiferous tubule degeneration ( J:85108 )
• about 3% were severely degenerated, on a 129S6/SvEvTac genetic background

reproductive system
seminiferous tubule degeneration ( J:85108 )
• about 3% were severely degenerated, on a 129S6/SvEvTac genetic background

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
04/30/2024
MGI 6.23 		The Jackson Laboratory